ABSTRACT
OBJECTIVE: To determine frequency of metabolic syndrome in patients with Schizophrenia, in a tertiary care armed forces setup
STUDY DESIGN: Cross sectional study
PLACE AND DURATION: Department of Psychiatry, PNS SHIFA, Karachi from October 2009 to April 2010
MATERIALS AND METHODS: Fifty six patients with Schizophrenia reporting for management in PNS SHIFA were enrolled as subjects. Demographic variables and other confounding variables were recorded in a structured Performa, Blood Pressure [BP] and Waist Circumference [WC] were measured while Fasting Plasma Glucose [FPG], Triglycerides [TAG] and HDL-Cholesterol [HDL-C] levels were estimated by routine methods in laboratory with quality assurance
RESULTS: More than half i.e.30 [53.6%] of subjects had Metabolic Syndrome [MS] as per ATP IIIA criteria. Further 25% [n=14]of subjects were positive for two components of MS. Low HDL-C levels were most prevalent component followed by hyperglycaemia, hypertriglyceridemia and increased WC while hypertension was least common component
CONCLUSION: Metabolic Syndrome and its various components are frequently co morbidity in patients with Schizophrenia
ABSTRACT
To assess psychological, social and occupational functioning of patients after seven years of diagnosis of schizophrenia using Global Assessment of Functioning [GAF] scale [DSM-IV Axis-V]. A cross sectional study. Department of Psychiatry, Military Hospital Rawalpindi from October 2007 to October 2008. This study included 30 patients who were retired military personnel invalided out of service with diagnosis of Schizophrenia between 1[st] Jan 2000 to 31[st] Dec 2001. After recording demographic data, patients underwent psychometric evaluation seven years after the diagnosis in 2007 and 2008 respectively for assessment of their psychological, social and occupational functioning using Global Assessment of Functioning [GAF] Scale [DSM - IV Axis V]. All subjects were male. Majority of the patients i.e. 14 [46.7%] patients had mild to moderate symptoms of the disease [GAF score 41 - 80]. Those having high income, employed and living in cities were associated with better global functioning. Schizophrenia continues to be a chronic disabling severe mental illness with deterioration in all aspects of functioning of patients